Kiri Honma

Organization・Title
Division of molecular epidemiology, Department of Molecular Microbiology and Immunology,
Special field
Immunology, Peditrics
Research themes
Analysis of the role of transcription factor, IRF-4, in immune responses

Course List

Medical virology, Infectious Disease Epidemiology, Medical Parasitology, Medical microbiology, Medical entomology, Medical immunology and genetics, Practical training for laboratory work

personal history

1986 Graduate Tsukuba Univ, school of Medicine                                 
1986-1998 Work in department of Pediatrics, Chiba Univ. School of Medicine  
1995-1997 Work in NIH as research fellow (Analysis of pathogenesis in autoimmune diseases)                     
1998-1999 Assistant proffesor, in department of microbiology and immunology, nippon medical school
1999-2005 Assistant professor in department of immunology, Nagasaki Univ. School of Medicine
2006-2012 Lecturer                                           
2012-present Associate professor in Leading graduate program

works/thesis

1. Mana Miyakoda, Daisuke Kimura, Kiri Honma, Kazumi Kimura, Masao Yuda, Katsuyuki Yui. Development of memory CD8+ T cells and their recall responses during blood-stage infection with Plasmodium berghei ANKA. Journal of Immunology,

2. Satoh T., Takeuchi O., Vandenbon A., Yasuda K., Tanaka Y., Kumagai Y., Miyake T., Matsushita K., Okazaki T., Saitoh T., Honma K., Matsuyama T., Yui K., Tsujimura T., Standley D., Nakanishi K., Nakai K., Akira S. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat. Immunol. 11: 936-944, 2010.189:4396-4404, 2012.

3. Honma K., Kimura D., Tominaga T., Miyakoda M., Matsuyama T., Yui K. Interferon regulatory factor-4 differentially regulates the production of Th2 cytokines in naive vs. effector/memory CD4+ T cells. Proc Natl Acad Sci USA: 105: 15890-15895, 2008.       

4. Honma, K., Udono, H., Kohno, T., Yamamoto, K., Ogawa, A., Takemori, T., Kumatori, A., Suzuki, S., Matsuyama, T., and Yui, K. Interferon regulatory factor-4 negatively regulates the production of proinflammatory cytokines by macrophages in response to LPS. Proc Natl Acad Sci USA 102: 16001-16006, 2005.                                     

5. Suzuki, S., K. Honma, T. Matsuyama, K. Suzuki, K. Toriyama, I. Akitoyo, K. Yamamoto, T. Suematsu, M. Nakamura, K. Yui, and A. Kumatori. 2004. Critical roles of interferon regulatory factor-4 in CD11brightCD8- dendritic cell development. Proc Natl Acad Sci USA 101: 8981-8986, 2004.