Culleton Richard Leighton

Organization・Title
Malaria Unit, Institute of Tropical Medicine, Nagasaki University Associate Professor
Special field
Malaria
Research themes
1)Interactions between Malaria parasite species
2)The immunology and Genetics of pre-erythrocytic stage malaria infections
3)Origins, Prevalence, and Population Genetics of P. Vivax in Africa
4)Plasmodium knowlesi; ecology of a zoonotic malaria parasite
5)Growth rates, virulence and transmission success in malaria
6)Urbanisation and malaria population genetics in africa
7)Other Projects

Homepage

http://www.tm.nagasaki-u.ac.jp/malariaunit

personal history

EDUCATION:

1996-2000 UNIVERSITY OF EDINBURGH, SCOTLAND, UK; BSC (HONS) (BIOLOGY, WITH ZOOLOGY HONOURS)
2001-2004 INSTITUTE OF CELL, ANIMAL AND POPULATION BIOLOGY, UNIVERSITY OF EDINBURGH, SCOTLAND, UK; PH.D.(GENETICS OF MALARIA PARASITES)

SCIENTIFIC EMPLOYMENT EXPERIENCE:

1996-2000 BSC STUDENT, ZOOLOGY, UNIVERSITY OF EDINBURGH
1998-2000 VOLUNTEER TAXONOMIST AT THE NATIONAL MUSEUM OF SCOTLAND, EDINBURGH
2000-2001 RESEARCH ASSISTANT, PROFESSOR DAVID WALLIKER (UNIVERSITY OF EDINBURGH)
2001-2004 WELLCOME TRUST PRIZE STUDENTSIP, PHD IN GENETICS OF MALARIA, UNIVERSITY OF EDINBURGH
2004-2005 WELLCOME TRUST RESEARCH ASSOCIATE WITH PROFESSOR RICHARD CARTER, UNIVERSITY OF EDINBURGH
2005-2008 JSPS INTERNATIONAL RESEARCH FELLOW, LABORATORY OF MALARIOLOGY, OSAKA UNIVERSITY, JAPAN
2008-2011 ASSISTANT PROFESSOR (TENURE TRACK), DEPARTMENT OF PROTOZOOLOGY, INSTITUTE OF TROPICAL MEDICINE (NEKKEN), NAGASAKI UNIVERSITY, JAPAN
2011-PRESENT ASSOCIATE PROFESSOR, HEAD, MALARIA UNIT, INSTITUTE OF TROPICAL MEDICINE (NEKKEN), NAGASAKI UNIVERSITY, JAPAN

works/thesis

1. Bispo N.A., Culleton R, Silva L.A. and Cravo P., A systematic in silico search for target similarity identifies several approved drugs with potential activity against the Plasmodium falciparum apicoplast, PLoS ONE (in press) 2013

2. Zhao H, Konishi A, Fujita Y, Yagi M, Ohata K, Aoshi T, Itagaki S, Sato S, Narita H, Abdelgelil N, Inoue M, Culleton R, Kaneko O, Nakagawa A, Horii T, Akira S, Ishii KJ, Coban C, Lipocalin 2 Bolsters Innate and Adaptive Immune Responses to Blood-Stage Malaria Infection by Reinforcing Host Iron Metabolism, Cell Host & Microbe, Vol. 12, Issue 5, pp. 705-716, 15 November 2012

3. Yahata K, Treeck M, Culleton R, Gilberger TW, Kaneko O. Time-lapse imaging of red blood cell invasion by the rodent malaria parasite Plasmodium yoelii. PLoS ONE (in press) 2012

4. Culleton R & Carter R, African Plasmodium vivax: Distribution and origins International Journal for Parasitology, 42 (12) 1091?1097, November 2012

5. Inoue M, Tang, J, Miyakoda M, Kaneko O, Yui K & Culleton R, The species specificity of immunity generated by live whole organism immunization with erythrocytic and pre-erythrocytic stages of rodent malaria parasites and implications for vaccine development. International Journal for Parasitology 42 (9) 859?870 August 2012

6. Culleton R & Ferreira P, Duffy Phenotype and Plasmodium vivax infections in Humans and Apes, Africa. Emerging Infectious Diseases Vol. 18, No. 10, October 2012

7. Tang J, Dai Y, Zhang H, Culleton RL, Liu Y, Zhao S, Wang X, Guan X, Kaneko O, Zhu Y. Positive diversifying selection on Plasmodium vivax RON2 protein. Parasitology Feb 10:1-7. 2012

8. Ferreira P & Culleton R, Dynamics of Plasmodium falciparum selection after artemether-lumefantrine treatment in Africa. Journal of Infectious Diseases Mar 28 2012

9. Culleton R & Carter R, Genetic Mapping of Virulence in Rodent Malarias, in "Evolution of Virulence in Eukaryotic Microbes", Editors, L. David Sibley, Barbara J. Howlett, and Joseph Heitman, Wiley-Blackwell 2012 (book chapter)

10. Stephens R, Culleton R, Lamb T. The contribution of Plasmodium chabaudi to our understanding of malaria Trends in Parasitology Feb;28(2):73-82 2012